Cyclerion Therapeutics, Inc. is classed by the SEC under Pharmaceutical Preparations (industry code 2834), based in Cambridge, MA. In its latest annual figures on file, for the fiscal year ended 2025-12-31, it reported revenue of $2 million and a loss of $4 million (its filed statements).
Pre-revenue companyPharmaceutical PreparationsCambridge, MAfilings since 20188 of 9 filed, 1 estimated
Three tenses, nine metrics. Unseen metrics stay unseen; the grade never fakes a number. Proxy era: provisional values, marked. Weighed as a pre-revenue company: no meaningful revenue on file yet (industry code 2834), so it is read as a pre-revenue company; the filing read can change it. All three tenses have at least two readings, so the archetype blend applies as printed.
The grade, in three tenses
Headline 4.8 out of ten, 8 of 9 metrics filed and 1 estimated: past 3.8 out of ten, present 5.2 out of ten, future 5.0 out of ten. The past asks what it actually did, the present what it is doing right now, the future what it is set up to do next.
The nine metrics
Surviving crises (past): 5.0 out of ten. 2 warning events since 2018; the latest 2022-11-29. 50th percentile among 497 sector filers. A production reading, recomputed from the filings on every data build (read from EDGAR 2026-10-12).
Track record (past): 2.5 out of ten. -2% a year over 6 filed years; profitable in 0 of 6. 25th percentile among 324 sector filers. A production reading, recomputed from the filings on every data build (read from EDGAR 2026-10-12).
Shareholder treatment (past): 4.7 out of ten. CrossAssetData estimate 4.7/10, confidence 35 of 100 (one part). 47th percentile among 463 sector filers. A CrossAssetData estimate, not a filed reading: one part, confidence 35 of 100; a filing that carries the missing parts replaces this estimate with the filed reading.
Financial health (present): 6.2 out of ten. ROE -39%: lost 39¢ per shareholder dollar. Leverage 9%: owes 9¢ per asset dollar. 62nd percentile among 472 sector filers. A production reading, recomputed from the filings on every data build (read from EDGAR 2026-10-12).
Industry position (present): 5.4 out of ten. top 46% of 314 in its family; net margin -170.1%. 54th percentile among 314 sector filers. A production reading, recomputed from the filings on every data build (read from EDGAR 2026-10-12).
Leadership (present): 3.5 out of ten. bottom 35% of 315 in its family for leadership; chief executive since 2024. 35th percentile among 315 sector filers. A production reading, recomputed from the filings on every data build (read from EDGAR 2026-10-09).
Room to expand (future): 4.7 out of ten. bottom 47% of 272 in its family for room to expand. 47th percentile among 272 sector filers. A production reading, recomputed from the filings on every data build (read from EDGAR 2026-10-12).
Growth drivers (future): 4.7 out of ten. bottom 47% of 307 in its family for growth drivers. 47th percentile among 307 sector filers. A production reading, recomputed from the filings on every data build (read from EDGAR 2026-10-12).
Expectations vs reality (future): 6.2 out of ten. top 38% of 234 in its family for expectations against reality. 62nd percentile among 234 sector filers. A production reading, recomputed from the filings on every data build (read from EDGAR 2026-10-12).
The filing record
Newest annual report: Form 10-K filed 2026-03-30 for the period ended 2025-12-31 (on EDGAR). Newest quarterly report: Form 10-Q filed 2026-08-04 for the period ended 2026-06-30 (on EDGAR). Newest results release: Form 8-K filed 2026-09-11 for the period ended 2026-09-08 (on EDGAR). Newest filing: Form SCHEDULE 13G/A, 2026-10-07. Filings on record since 2018. Read from EDGAR 2026-10-12.
Where the revenue comes from
Product and service lines in fiscal 2025: License Agreement 48%, Purchase Agreement 39%, Option Agreement 13%. As tagged in its annual report (Form 10-K, filed 2026-03-31).
Who runs it
Violin, Jonathan (Chief Executive Officer and President Exhibit 24 - Power of Attorney); Graul, Regina Margaret (President and Chief Executive Officer); Hecht, Peter M (Chief Executive Officer); Vignola, Mark J. (Chief Financial Officer); Chicko, Rhonda M. (Chief Financial Officer); Leoni, Matthew James (Chief Medical Officer); Fairmount, Funds Management Llc (director); Fairmount, Healthcare Co-Invest Vi L.p. (director); Fairmount, Healthcare Fund II L.p. (director); Gottesdiener, Andrew (director); and 5 more. 15 officers and directors have filed their own trades in the last fifteen months, names and titles as filed with the SEC, through 2026-09-30.
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